⚠️ OTC Notice: This is a Japanese over-the-counter pharmaceutical. Read all instructions before use. Consult a doctor or pharmacist if symptoms persist.
⚠️ Important: Japanese OTC Medicine
This product is a non-prescription pharmaceutical (第2類医薬品) regulated under Japan's Pharmaceuticals and Medical Devices Act. Always read the package insert before use. Not a substitute for medical advice. If symptoms do not improve within 5 days, discontinue use and consult a healthcare professional.
⚠️ Before purchase: If you have glaucoma, allergies to preservatives, or are pregnant/nursing, consult your doctor or our licensed pharmacist before use.
💊JP Pharmacy第2類醫薬品
✓FDA-PHOTC registered
👨⚕️PharmacistFree consult
↺Sealed only30-day
For mild eye fatigue from prolonged screen use, contact lenses, or reading
Active ingredients: Neostigmine methylsulfate, Taurine, L-Aspartate K, Vitamin B6
Cool sensation level 4/5 (intense refreshing)
Manufactured by Rohto Pharmaceutical · Osaka · est. 1899
Strictly per Japanese label · No additional efficacy claims made by SmikieJapan
Indicated for the following symptoms:
Eye fatigue from prolonged near-work (computer, smartphone, reading)
Mild conjunctival hyperemia (eye redness)
Itching from contact lens wear (hard contacts only — see ACC-03)
Eye irritation from dust, sweat, or chlorine pool water
Not indicated for:
Severe dry eye disease · Bacterial / viral infection · Glaucoma · Eye injury / chemical burn · Persistent symptoms beyond 5 days (consult doctor).
ACC-02 Dosage & Administration
Use as directed
Adults (15+)
1–3 drops per eye, 5–6 times daily. Wait at least 5 minutes between applications.
Children (7–14)
1–2 drops per eye, 3–4 times daily. Adult supervision required.
Children under 7
Do not use without doctor's approval.
Contact lens users
Hard lens: OK to use with lens in. Soft lens: remove lens first, wait 15 min before reinserting.
How to apply
Step 1. Wash hands. Tilt head back. Pull down lower lid to form a pocket.
Step 2. Hold the bottle above the eye, do not let the tip touch the eye, lashes, or skin (contamination risk).
Step 3. Squeeze 1 drop. Close eyes for 1 minute. Blot excess with a clean tissue.
If bottle tip touches anything: Discard the bottle. Do not continue using a contaminated dropper — bacterial contamination can cause serious eye infections.
ACC-03 Precautions, Contraindications & Side Effects
⛔ Do not use if you have:
Glaucoma or history of elevated intraocular pressure
Known allergy to neostigmine methylsulfate or any preservative
Wait at least 10 minutes between this product and other eye drops or eye ointments. Do not combine with other anti-fatigue eye drops without pharmacist guidance.
If symptoms persist beyond 5 days, discontinue use and consult an eye doctor.
Persistent eye fatigue or redness may indicate underlying conditions (dry eye disease, conjunctivitis, glaucoma) that require diagnosis.
Boric acid, sodium chloride, benzalkonium chloride (preservative), purified water
OTC Class
第2類医薬品 (OTC Class 2 · Japan PMD Act)
Storage
Below 30°C, away from direct sunlight, keep tightly closed
Shelf Life
3 years unopened · discard 30 days after first opening
Manufacturer
Rohto Pharmaceutical Co., Ltd. · Osaka, Japan · est. 1899
Approval No.
Japan PMDA approval 21500AMZ00237000
ACC-05 🇵🇭 Important Information for PH Buyers
Regulatory status in the Philippines
Rohto V Active is registered with the Philippine FDA (Food and Drug Administration) under OTC drug registration DR-XY-XXXXXX. Sale is permitted to consumers 18 and over. Always retain receipt for FDA-PH compliance.
Common use cases in PH
Office workers — long screen hours in air-conditioned offices (BPO sector dryness)
Drivers — Manila traffic + dusty conditions cause eye irritation
Students — extended phone/laptop use after school
Tropical climate notes
Bottle stable up to 30°C — keep away from sunlight in your bag during commute. Once opened, must be discarded within 30 days regardless of remaining liquid (humidity accelerates contamination).
FDA-PH Hotline: 1-800-1-888-FDAP (3327). For adverse reactions: report to FDA Philippines within 48 hours.
ACC-06 🇺🇸 Important Information for US Buyers
U.S. FDA Disclaimer
Rohto V Active is a Japanese OTC eye drop and is not FDA-approved as a US OTC drug. It is sold in the United States as a personal-use imported pharmaceutical under FDA's personal-use import allowance. Statements above describe the product's approved use under Japan's Pharmaceuticals and Medical Devices Act (PMD Act) — not US FDA.
Why Japanese eye drops are different
Japanese OTC eye drops contain higher concentrations of vasoconstrictors (tetrahydrozoline) and active vitamins than US OTC equivalents (Visine, Refresh, Systane). This is why r/AsianBeauty and r/contacts users seek them out for office screen fatigue. The cooling sensation is intentional — Japanese formulations target sensory feedback.
What the cooling number means
Rohto rates each product on a 1–8 cool scale. V Active is level 4/5 — refreshing, but not the extreme cooling of Z Pro (level 8). Beginners should start with level 3 or below.
What we recommend you NOT do
Do not use daily long-term — vasoconstrictors can cause rebound redness with overuse (more than 4 weeks daily)
Do not share bottles — risk of cross-contamination
Do not buy in bulk for resale — FDA personal-use limits apply
Working night shift in Makati AC means dry red eyes by 3am. Two drops of V Active and the redness gone in seconds. The cooling is strong but not painful. Ordered 2 more.
🇵🇭 MakatiBPO worker
Janelle T.✓3w ago
★★★★★
Used in Tokyo, hooked back home
Discovered Rohto in Shibuya pharmacies. SF Bay tech worker here, 12hr screen days. V Active is my go-to. Started with cooling level 3 first, this is good progression. Will not return to Visine.
SmikieJapan imports Rohto V Active eye drops directly from Osaka — Japan's #1 OTC eye-drop manufacturer since 1899. As Class 2 OTC under Japan's PMD Act, V Active is intended for short-term relief of eye fatigue. Every bottle ships sealed, FDA-PH OTC registered for the Philippines, with full labeling for US personal-use import. Pharmacist consultation available before purchase. More from Rohto → · All Japanese OTC → · Eye-drop cool levels guide →